The always-interesing Robin Hanson talks about brain uploads here:
What do you think? In a world of machine intelligence, even where the minds are emulations of meat-generated human brains, how will the face of euvoluntary exchange adjust? With insanely fast clock speeds, uploads are likely to quickly outstrip traditional humans in population as well as wealth. Our descendants could end up in a world where BATNA disparity is far beyond what we encounter these days. How will moral intuitions change? How will the institutions of trade adapt? Will the basic lessons of economics still apply?